You'll need four coordinating patterns to start, but you can always add more or use fewer depending on the size of your card and the size of the patterns themselves.
Vary the size of each panel so they'll stack and overlap in interesting ways, keeping the sentiment close to the center. This will balance out the card and let you see as much of the patterns as possible.
Then use two tiny embellishments in two of the corners and two larger embellishments on the opposite corners near the sentiment.
The hand-stamped phrase stays near the middle of the card, and it is accented with two 3D ladybugs made from chipboard.
Finally, there are two blue gems in the opposite corners to balance it all out.
For more great layout ideas, come visit my Etsy shop! You'll find hundreds of cards, journals and paper crafts, so don't be surprised if you walk away with a few gifts, too.